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1

Age-Associated Epigenetic Upregulation of the FKBP5 Gene Selectively Impairs Stress Resiliency

Sabbagh, Jonathan J., O'Leary, John C., Blair, Laura J., Klengel, Torsten, Nordhues, Bryce A., Fontaine, Sarah N., Binder, Elisabeth B., Dickey, Chad A., Yoshikawa, Takeo

Journal:

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

2

Imbalance of Hsp70 family variants fosters tau accumulation

Jinwal, U. K., Akoury, E., Abisambra, J. F., O'Leary, J. C., Thompson, A. D., Blair, L. J., Jin, Y., Bacon, J., Nordhues, B. A., Cockman, M., Zhang, J., Li, P., Zhang, B., Borysov, S., Uversky, V. N.,

Journal:

The FASEB Journal

Year:

2013

Language:

english

File:

PDF, 534 KB

english, 2013

3

Inhibition of Both Hsp70 Activity and Tau Aggregation In Vitro Best Predicts Tau Lowering Activity of Small Molecules

Martin, Mackenzie D., Baker, Jeremy D., Suntharalingam, Amirthaa, Nordhues, Bryce A., Shelton, Lindsey B., Zheng, Dali, Sabbagh, Jonathan J., Haystead, Timothy A.J., Gestwicki, Jason E., Dickey, Chad

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 3.94 MB

english, 2016

4

Evidence for a Role of VIPP1 in the Structural Organization of the Photosynthetic Apparatus in Chlamydomonas

Nordhues, A., Schottler, M. A., Unger, A.-K., Geimer, S., Schonfelder, S., Schmollinger, S., Rutgers, M., Finazzi, G., Soppa, B., Sommer, F., Muhlhaus, T., Roach, T., Krieger-Liszkay, A., Lokstein, H.

Journal:

Year:

2012

Language:

english

File:

PDF, 2.26 MB

english, 2012

5

Hsp90 activator Aha1 drives production of pathological tau aggregates

Shelton, Lindsey B., Baker, Jeremy D., Zheng, Dali, Sullivan, Leia E., Solanki, Parth K., Webster, Jack M., Sun, Zheying, Sabbagh, Jonathan J., Nordhues, Bryce A., Koren, John, Ghosh, Suman, Blagg, Br

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

6

Transformative Learning and Professional Identity Formation During International Health Electives

Sawatsky, Adam P., Nordhues, Hannah C., Merry, Stephen P., Bashir, M. Usmaan, Hafferty, Frederic W.

Journal:

Academic Medicine

Year:

2018

Language:

english

File:

PDF, 1.81 MB

english, 2018

7

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

Blair, Laura J., Nordhues, Bryce A., Hill, Shannon E., Scaglione, K. Matthew, O’Leary, John C., Fontaine, Sarah N., Breydo, Leonid, Zhang, Bo, Li, Pengfei, Wang, Li, Cotman, Carl, Paulson, Henry L., M

Journal:

Journal of Clinical Investigation

Year:

2013

Language:

english

File:

PDF, 4.39 MB

english, 2013

8

Application of quantitative immunoprecipitation combined with knockdown and cross-linking to Chlamydomonas reveals the presence of vesicle-inducing protein in plastids 1 in a common complex with chloroplast HSP90C

Heinrich Heide, André Nordhues, Friedel Drepper, Sabine Nick, Miriam Schulz-Raffelt, Wolfgang Haehnel, Michael Schroda

Journal:

Year:

2009

Language:

english

File:

PDF, 220 KB

english, 2009

9

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes

Ehrchen, J., Steinmuller, L., Barczyk, K., Tenbrock, K., Nacken, W., Eisenacher, M., Nordhues, U., Sorg, C., Sunderkotter, C., Roth, J.

Journal:

Year:

2006

Language:

english

File:

PDF, 242 KB

english, 2006

10

‘RED’ groups: a bottom‐up approach to wellness

Nordhues, Hannah C, Haddox, Candace L, Kashiwagi, Deanne T, Kubey, Alan A

Journal:

The Clinical Teacher

Year:

2019

File:

PDF, 193 KB

2019

11

Autonomy and Professional Identity Formation in Residency Training: A Qualitative Study

Sawatsky, Adam P., Santivasi, Wil L., Nordhues, Hannah C., Vaa, Brianna E., Ratelle, John T., Beckman, Thomas J., Hafferty, Frederic W.

Journal:

Medical Education

Year:

2020

File:

PDF, 14.71 MB

2020

12

Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action

Karagöz, G. Elif, Duarte, Afonso M.S., Akoury, Elias, Ippel, Hans, Biernat, Jacek, Morán Luengo, Tania, Radli, Martina, Didenko, Tatiana, Nordhues, Bryce A., Veprintsev, Dmitry B., Dickey, Chad A., Ma

Journal:

Year:

2014

Language:

english

File:

PDF, 2.41 MB

english, 2014

13

UNUSUAL CAUSES AND COURSES OF LEFT VENTRICULAR PSEUDOANEURYSMS

Jain, C. Charles, Sabbagh, Abdallah El, Nordhues, Ben, Killu, Ammar, Rihal, Charanjit

Journal:

Journal of the American College of Cardiology

Year:

2019

Language:

english

File:

PDF, 243 KB

english, 2019

14

BILEAFLET MITRAL VALVE PROLAPSE AND THE RISK OF VENTRICULAR DYSRHYTHMIAS AND DEATH

Nordhues, Ben, Siontis, Konstantinos, Scott, Christopher, Nkomo, Vuyisile, Ackerman, Michael, Asirvatham, Samuel, Noseworthy, Peter

Journal:

Journal of the American College of Cardiology

Year:

2016

Language:

english

File:

PDF, 400 KB

english, 2016

15

Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD

Sabbagh, Jonathan J., Cordova, Ricardo A, Zheng, Dali, Criado-Marrero, Marangelie, Lemus, Andrea, Li, Pengfei, Baker, Jeremy D., Nordhues, Bryce A., Darling, April L., Martinez-Licha, Carlos, Rutz, Da

Journal:

ACS Chemical Biology

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

16

Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement

Fontaine, Sarah N., Rauch, Jennifer N., Nordhues, Bryce A., Assimon, Victoria A., Stothert, Andrew R., Jinwal, Umesh K., Sabbagh, Jonathan J., Chang, Lyra, Stevens, Stanley M., Zuiderweg, Erik R. P.,

Journal:

Journal of Biological Chemistry

Year:

2015

Language:

english

File:

PDF, 3.70 MB

english, 2015

17

Evidence for a Role of VIPP1 in the Structural Organization of the Photosynthetic Apparatus in Chlamydomonas

André Nordhues, Mark Aurel Schöttler, Ann-Katrin Unger, Stefan Geimer, Stephanie Schönfelder, Stefan Schmollinger, Mark Rütgers, Giovanni Finazzi, Barbara Soppa, Frederik Sommer, Timo Mühlhaus, Thomas

Journal:

Year:

2012

Language:

english

File:

PDF, 5.20 MB

english, 2012

18

MANIPULATIONS AND STOCK EXCHANGE TRANSACTIONS: THE APPLICATION OF THE GERMAN CRIMINAL CODE AND INSIDER DEALING PROVISIONS

NORDHUES, HANS‐GÜNTHER

Journal:

Journal of Financial Regulation and Compliance

Year:

1995

Language:

english

File:

PDF, 301 KB

english, 1995

19

NMR Characterization of the Type III Secretion System Tip Chaperone Protein PcrG of Pseudomonas aeruginosa

S. Chaudhury, B. A. Nordhues, K. Kaur, N. Zhang, R. N. De Guzman

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

20

Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma

Stothert, Andrew R., Suntharalingam, Amirthaa, Tang, Xiaolan, Crowley, Vincent M., Mishra, Sanket J., Webster, Jack M., Nordhues, Bryce A., Huard, Dustin J. E., Passaglia, Christopher L., Lieberman, R

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 4.05 MB

english, 2017

21

Prevalence and Clinical Correlates of Aortic Dilation in Hypertrophic Cardiomyopathy

Geske, Jeffrey B., Nordhues, Benjamin D., Orme, Nicholas M., Tajik, A. Jamil, Spittell, Peter C., Ommen, Steve R.

Journal:

Journal of the American Society of Echocardiography

Year:

2020

File:

PDF, 3.11 MB

2020

22

TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells

Viemann, D., Goebeler, M., Schmid, S., Nordhues, U., Klimmek, K., Sorg, C., Roth, J.

Journal:

Journal of Leukocyte Biology

Year:

2006

Language:

english

File:

PDF, 387 KB

english, 2006

23

[International Review of Cell and Molecular Biology] Volume 285 || New Insights into the Roles of Molecular Chaperones in Chlamydomonas and Volvox

Nordhues, André

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

24

Protein Cross-Linking Capillary Electrophoresis for Protein–Protein Interaction Analysis

Ouimet, Claire M., Shao, Hao, Rauch, Jennifer N., Dawod, Mohamed, Nordhues, Bryce, Dickey, Chad A., Gestwicki, Jason E., Kennedy, Robert T.

Journal:

Analytical Chemistry

Year:

2016

Language:

english

File:

PDF, 628 KB

english, 2016

25

Tau Accumulation Activates the Unfolded Protein Response by Impairing Endoplasmic Reticulum-Associated Degradation

Abisambra, J. F., Jinwal, U. K., Blair, L. J., O'Leary, J. C., Li, Q., Brady, S., Wang, L., Guidi, C. E., Zhang, B., Nordhues, B. A., Cockman, M., Suntharalingham, A., Li, P., Jin, Y., Atkins, C. A.,

Journal:

Journal of Neuroscience

Year:

2013

Language:

english

File:

PDF, 3.40 MB

english, 2013

26

Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis

Selenica, Maj-Linda B, Davtyan, Hayk, Housley, Steven B, Blair, Laura J, Gillies, Anne, Nordhues, Bryce A, Zhang, Bo, Liu, Joseph, Gestwicki, Jason E, Lee, Daniel C, Gordon, Marcia N, Morgan, Dave, Di

Journal:

Journal of Neuroinflammation

Year:

2014

Language:

english

File:

PDF, 1.56 MB

english, 2014

27

Calredoxin represents a novel type of calcium-dependent sensor-responder connected to redox regulation in the chloroplast

Hochmal, Ana Karina, Zinzius, Karen, Charoenwattanasatien, Ratana, Gäbelein, Philipp, Mutoh, Risa, Tanaka, Hideaki, Schulze, Stefan, Liu, Gai, Scholz, Martin, Nordhues, André, Offenborn, Jan Niklas, P

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.83 MB

english, 2016

28

Graduate medical education competencies for international health electives: A qualitative study

Nordhues, Hannah C., Bashir, M. Usmaan, Merry, Stephen P., Sawatsky, Adam P.

Journal:

Medical Teacher

Year:

2017

Language:

english

File:

PDF, 1.31 MB

english, 2017

29

The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease

Blair, Laura, Nordhues, Bryce, Hill, Shannon, Scaglione, K. Matthew, O'Leary, John, Breydo, Leonid, Bo, Zhang, Li, Pengfei, Wang, Lily, Cotman, Carl, Paulson, Henry, Muschol, Martin, Uversky, Vladimir

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

30

Dealing With Patient Death on International Health Electives

Bashir, M. Usmaan, Nordhues, Hannah C., Merry, Stephen P., Sawatsky, Adam P.

Journal:

Academic Medicine

Year:

2019

File:

PDF, 203 KB

2019

31

Bileaflet Mitral Valve Prolapse and Risk of Ventricular Dysrhythmias and Death

NORDHUES, BENJAMIN D., SIONTIS, KONSTANTINOS C., SCOTT, CHRISTOPHER G., NKOMO, VUYISILE T., ACKERMAN, MICHAEL J., ASIRVATHAM, SAMUEL J., NOSEWORTHY, PETER A.

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2016

Language:

english

File:

PDF, 492 KB

english, 2016

32

A Protocol for the Identification of Protein-protein Interactions Based on 15N Metabolic Labeling, Immunoprecipitation, Quantitative Mass Spectrometry and Affinity Modulation

Schmollinger, Stefan, Strenkert, Daniela, Offeddu, Vittoria, Nordhues, André, Sommer, Frederik, Schroda, Michael

Journal:

Journal of Visualized Experiments

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012

33

The disorderly conduct of Hsc70 and its interaction with the Alzheimer’s related Tau protein

Taylor, Isabelle R., Ahmad, Atta, Wu, Taia, Nordhues, Bryce A., Bhullar, Anup, Gestwicki, Jason E., Zuiderweg, Erik R.P.

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.19 MB

english, 2018

34

‘RED’ groups: a bottom‐up approach to wellness

Nordhues, Hannah C, Haddox, Candace L, Kashiwagi, Deanne T, Kubey, Alan A

Journal:

The Clinical Teacher

Year:

2019

Language:

english

File:

PDF, 193 KB

english, 2019

35

The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate

Srirupa Chatterjee, Dalian Zhong, Bryce A. Nordhues, Kevin P. Battaile, Scott Lovell, Roberto N. De Guzman

Journal:

Protein Science

Year:

2011

Language:

english

File:

PDF, 1.88 MB

english, 2011

36

NMR Characterization of the Interaction of the Salmonella Type III Secretion System Protein SipD and Bile Salts ,

Wang, Yu, Nordhues, Bryce A., Zhong, Dalian, De Guzman, Roberto N.

Journal:

Year:

2010

Language:

english

File:

PDF, 2.98 MB

english, 2010

37

Sind Antidepressiva bei leichter Depression indiziert?

Nordhues, Philipp, Bschor, Tom

Journal:

DNP - Der Neurologe und Psychiater

Year:

2014

Language:

german

File:

PDF, 237 KB

german, 2014

38

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

Abisambra, Jose, Jinwal, Umesh, Blair, Laura, O'Leary, John, Li, Qingyou, Brady, Sarah, Wang, Lily, Guidi, Chantal, Zhang, Bo, Nordhues, Bryce, Cockman, Mathew, Suntharalingham, Amirthaa, Li, Pengfei,

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 73 KB

english, 2013

39

Initial Toxicities of Prostate Cancer Patients Treated with Uniform Scanning Proton Therapy

S.R. Keole, O. Zeidan, A. Mascia, C. Vargas, K. Prabhu, G. Larson, E. Nordhues, R. Gaston, J. Taylor

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 47 KB

english, 2011

40

The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics

Fontaine, S. N., Martin, M. D., Akoury, E., Assimon, V. A., Borysov, S., Nordhues, B. A., Sabbagh, J. J., Cockman, M., Gestwicki, J. E., Zweckstetter, M., Dickey, C. A.

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

41

PREVALENCE AND CLINICAL CORRELATES OF AORTIC DILATION IN HYPERTROPHIC CARDIOMYOPATHY

Nordhues, Ben, Geske, Jeffrey, Orme, Nicholas, Tajik, A. Jamil, Spittell, Peter, Ommen, Steve

Journal:

Journal of the American College of Cardiology

Year:

2020

File:

PDF, 134 KB

2020

42

Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy

Blair, Laura J, Frauen, Haley D, Zhang, Bo, Nordhues, Bryce A, Bijan, Sara, Lin, Yen-Chi, Zamudio, Frank, Hernandez, Lidice D, Sabbagh, Jonathan J, Selenica, Maj-Linda B, Dickey, Chad A

Journal:

Acta Neuropathologica Communications

Year:

2015

Language:

english

File:

PDF, 9.91 MB

english, 2015

43

DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative‐associated proteins

Fontaine, Sarah N, Zheng, Dali, Sabbagh, Jonathan J, Martin, Mackenzie D, Chaput, Dale, Darling, April, Trotter, Justin H, Stothert, Andrew R, Nordhues, Bryce A, Lussier, April, Baker, Jeremy, Shelton

Journal:

The EMBO Journal

Year:

2016

Language:

english

File:

PDF, 1.86 MB

english, 2016

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